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ea0070oc9.2 | Reproductive and Developmental Endocrinology | ECE2020

Kisspeptin as a biomarker for pregnancy complications

Phylactou Maria , Abbara Ali , Chia Eng Pei , Al-Memar Maya , Comninos Alexander , Nadir Rans , Izzi-Engbeaya Chioma , Clarke Sophie , Mills Edouard , Sykes Mark , Pacuszka Ewa , Yang Lisa , Fourie Hanine , Bech Paul , Kelsey Tom , Bourne Tom , Dhillo Waljit

Background: Placentation (invasion of the placenta into the maternal endometrium of pregnancy known as the decidua) is hypothesised to be critical for healthy placental function and is abnormal in two thirds of miscarriage. Kisspeptin has emerged as a putative regulator of physiological placentation; it is highly expressed in placental syncitio-trophoblasts, whereas its receptor is expressed in both syncitio- and cyto-trophoblasts, such that kisspeptin is hypothesized to play ...

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ea0065op5.4 | Reproductive Endocrinology and Biology | SFEBES2019

Kisspeptin as a novel biomarker for pregnancy complications

Phylactou Maria , Abbara Ali , Al-Memar Maya , Eng Pei Chia , Comninos Alexander N , Izzi-Engbeaya Chioma , Clarke Sophie A , Mills Edouard , Nadir Rans , Sykes Mark , Pacuszka Ewa , Yang Lisa , Fourie Hanine , Bech Paul , Kelsey Tom W , Bourne Tom , Dhillo Waljit S

Background: Placentation (invasion of the placenta into the maternal endometrium) is hypothesised to be critical for healthy placental function and is abnormal in two thirds of miscarriages. Kisspeptin has emerged as a putative regulator of physiological placentation; it is highly expressed in placental syncytiotrophoblasts and could play an important paracrine role in the regulation of placentation. Circulating kisspeptin levels are considerably raised during healthy pregnanc...

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Endocrine Abstracts

Kisspeptin as a biomarker for pregnancy complications

Kisspeptin as a novel biomarker for pregnancy complications

BiosciAbstracts